Cannabinoids can modulate these immune reactions, with some studies suggesting that they can act as either an immunosuppressant, but also immune-boosting effects. In other words, on the one hand, cannabinoids have the potential to relieve symptoms of patients with over-active immune systems, suffering from autoimmune diseases and chronic inflammation.  On the other hand, they also can help people suffering from immunodeficiency disorders such as HIV, through its ability to boost white blood counts.

 

This makes for a complicated and dichotomous relationship between cannabinoids and the immune system that is still poorly understood.  In addition, the actions of cannabinoids like cannabidiol (CBD) and tetrahydrocannabinol (THC) are mediated primarily by the...

The authors of the study said these findings are important in light of major policy changes surrounding the production and sale of cannabis products, as well as increases in the number of people entering treatment for cannabis use disorders and the absence of recommended treatments for this.

Dr Tom Freeman, the study's lead author and Director of the Addiction and Mental Health Group at the University of Bath, UK, said: "Our study provides the first causal evidence to support cannabidiol, or CBD, as a treatment for cannabis use disorders.

“This is encouraging, as there are currently no drug treatments for cannabis addiction.

“CBD products are widely available in many countries but we would not advise people to self-medicate with these products. People with concerns about their cannabis use should always speak to a healthcare professional in the first instance."

Endocannabinoids, Phytocannabinoids & MS

All of us have something known as an endocannabinoid system (ECS) consisting of receptors, neurotransmitters known as endocannabinoids, and enzymes that break these down once they served their purpose (read more about it here ). 

However, endocannabinoids are a special type of neurotransmitter that are able to not only affect “receiver” neurons, but also “sender” neurons.  When a postsynaptic neuron gets triggered, endocannabinoid production is activated, from where they travel “backwards” up the axon towards the presynaptic neuron, functioning like a dimmer-switch that suppresses neurotransmitter release and neural activity.  Essentially, this means that the way in which neural impulses are sent, neurotransmitters are released, and how these are processed by the CNS is primarily mediated by the ECS.

The extracts were low in THC, a cannabinoid (like CBD) found in the marijuana plant that induces a ‘high’.

The researchers then tested the effect the extracts had an angiotensin-converting enzyme 2(ACE2) - the receptors needed for the virus to enter cells in the body.

The results showed hemp extracts high in CBD may help block protein that give a “gateway” for COVID-19 to enter a person’s cells.

CBD Oil Dosage for Sleep

In an early study on the effects of CBD on sleep, researchers found dosage that people who do not suffer from sleeping disorders, needed very high doses of around the 600 mg mark while insomniacs only needed doses of a 150 mg to 160 mg of CBD to induce sleep. Therefore, it is suggested to start off with a dose of 40 mg, gradually working up to anywhere between...

As the popularity of medical cannabis and hemp-infused products increases, so too are the different ways in which you can take it - from oils and tinctures, to gummies, creams, vapes, teas, and even toothpicks. 

 

No wonder then that an increasing number of people are starting to question the efficacy if what many consider more gimmicky products. But also, what IS the best and most effective way to take medical cannabis and hemp products?

 A child with ADHD has differences in the way in which their brain develops, where the resulting pattern of brain activity affects the persons ability to sustain attention and/or exert self control.  This often leads to an inability to sit still...

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