The Role of the Endocannabinoid System in Pain & Inflammation

The role of the endocannabinoid system (ECS) in pain control and symptom relief has been repeatedly demonstrated due to a certain level of independent control and mediation it exerts in the central nervous system and pain signalling system.  Data from various animal studies and clinical trials have shown that the ECS and its primary ligands (a.k.a. endocannabinoids) play a role in pain and pain relief by mediating not only the CB1 and CB2 cannabinoid receptors but also other receptors involved with pain signalling. 

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