CBD and COVID19 - a look at some recent research.
CBD has been studied for its numerous health benefits, including anxiety, pain relief and skin-related issues. And now new research has added another possible benefit to the list - the cannabinoid could be key in the fight against coronavirus.
Scientists from the University of Lethbridge in Alberta, Canada have tested whether or not marijuana compounds can protect against the coronavirus infection.
Looking at 400 cannabis strains they focused on around a dozen that showed promise in preventing COVID-19 “hijacking” cells in the human body.
The study, conducted in April, was published in peer journal Preprints and the results were released in a study titled ‘In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues’.
As part of the study, the researchers used 3D models of oral, airway and intestinal tissues coupled with a sample of high CBD extracts from cannabis sativa plants.
The extracts were low in THC, a cannabinoid (like CBD) found in the marijuana plant that induces a ‘high’.
The researchers then tested the effect the extracts had an angiotensin-converting enzyme 2(ACE2) - the receptors needed for the virus to enter cells in the body.
The results showed hemp extracts high in CBD may help block protein that give a “gateway” for COVID-19 to enter a person’s cells.
Dr. Igor Kovalchuk, CEO of Pathway Rx and holder, told The Calgary Herald: “A number of them have reduced the number of [virus] receptors by 73 percent, the chance of it getting in is much lower.
“If they can reduce the number of receptors, there's much less chance of getting infected.”
Of course, more evidence is needed to substantiate these findings, but the results are promising, particularly with no successful vaccine or treatment currently available.
Dr Kovalchuk said much more research would be necessary before they understand precisely whether CBD, THC or some combination of ingredients is causing the reduction in receptors.
He added researchers would likely focus on understanding how CBD works, as it can be taken frequently and in high-concentration without getting a person high.
But CBD may be able to help in another way in this current climate - it could help with social distancing-related anxiety.
The National Institute on Drug Abuse (NIDA) says CBD has been shown to reduce stress in animals such as rats, in particular generalised anxiety disorder.
Generalised anxiety order is described as a feeling of unease, such as worry or fear, that can be mild or severe.
They were observed as having lower behaviour signs of anxiety and improvements in physical signs, such as increased heart rate.
What other diseases could CBD help with?
Some studies have suggested CBD can help in the prevention of cancer.
One study published in 2015 found a positive relationship between cannabis and bladder cancer. https://pubmed.ncbi.nlm.nih.gov/25623697/?dopt=Abstract
After adjusting certain factors, researchers found cannabis users had a 45-percent lower risk of developing bladder cancer.
Smoking cannabis can increase the risk of tobacco-related cancers, but ingesting CBD extract offers a good alternative.
In some cases, cannabinoids have been shown to help in the fight against cancer.
In a 2016 study, researchers found cannabinoids inhibited the growth of many different types of tumour cell in both test tubes and animal models. http://www.phmd.pl/api/files/view/117062.pdf
CBD could also help treat or prevent heart disease.
High blood pressure is a leading risk for heart disease and high blood pressure can rise under stress. But some research suggests how CBD can help.
A study carried out in 2017 subjected healthy human volunteers to stress and then gave them a dose of CBD. https://insight.jci.org/articles/view/93760
The CBD was found to lower their blood pressure as compared to volunteers given a placebo.
Having heart disease can increase a person’s risk of having a stroke - a serious and life-threatening medical condition that occurs when the blood supply to part of the brain is cut off.
But a 2010 review found CBD may help protect stroke patients from brain damage and even aid recovery by boosting brain function. https://www.mdpi.com/1424-8247/3/7/2197
A review published in 2017 also found CBD increased cerebral blood flow during a stroke. https://www.frontiersin.org/articles/10.3389/fphar.2017.00081/full
Is it safe to take CBD?
While CBD is still undergoing extensive research, it’s been shown to be well-tolerated and hundreds of positive user reviews can be found online.
One cause for concern when it comes to CBD is unreliability is the purity and dosage in some products.
Kanaco offers a range of lab tested CBD products from oils to hemp tea along with CBD vape cartridges and soft gel capsules. Strengths include 250mg, 500mg, 1,000mg, 2,000mg and 3000mg.
To make sure you select a trusted CBD company we recommend buyers to do the following
1) Look for companies that have top rated reviews. See why Kanaco has 4.9 stars.
2) Buy CBD from companies that laboratory test their CBD .
3) Be suspicious of big health claims.
4) Word of mouth is still the best way to find great products and services -ask a friend for a personal recommendation.
5) Choose a company that has been operating for a long time.
Kanaco does not sell CBD as a medicinal product and we suggest that anyone looking to buy or take CBD does consult with a doctor first. Any mention in this article of potential health benefits and diseases is for the purpose of discussing research that has shown potential use cases for CBD. It should be made clear that a lot of these research studies are inclusive and we recommend consulting with a healthcare expert before trying any type of alternative medicine.