Endocannabinoids, Phytocannabinoids & MS

All of us have something known as an endocannabinoid system (ECS) consisting of receptors, neurotransmitters known as endocannabinoids, and enzymes that break these down once they served their purpose (read more about it here ). 

However, endocannabinoids are a special type of neurotransmitter that are able to not only affect “receiver” neurons, but also “sender” neurons.  When a postsynaptic neuron gets triggered, endocannabinoid production is activated, from where they travel “backwards” up the axon towards the presynaptic neuron, functioning like a dimmer-switch that suppresses neurotransmitter release and neural activity.  Essentially, this means that the way in which neural impulses are sent, neurotransmitters are released, and how these are processed by the CNS is primarily mediated by the ECS.

The extracts were low in THC, a cannabinoid (like CBD) found in the marijuana plant that induces a ‘high’.

The researchers then tested the effect the extracts had an angiotensin-converting enzyme 2(ACE2) - the receptors needed for the virus to enter cells in the body.

The results showed hemp extracts high in CBD may help block protein that give a “gateway” for COVID-19 to enter a person’s cells.

How CBD interacts with other medications, contraindications & side effects

The safety profile of cannabidiol (CBD) has been extensively researched.  Data from studies, laboratory experiments and clinical trials all show that CBD is well tolerated in both animals and humans, even at extremely high dosages.  In fact, to date, not a single report of a CBD overdose or death has been reported.

Let's take a look at how cannabis and black lives intertwine and what needs to change. 

A more up to date 2020 analysis by the ACLU concluded: “Black people are 3.64 times more likely than white people to be arrested for marijuana possession, notwithstanding comparable usage rates.”

The authors reported: “In every single state, black people were more likely to be arrested for marijuana possession, and in some states, Black people were up to...

CBD Oil Dosage for Sleep

In an early study on the effects of CBD on sleep, researchers found dosage that people who do not suffer from sleeping disorders, needed very high doses of around the 600 mg mark while insomniacs only needed doses of a 150 mg to 160 mg of CBD to induce sleep. Therefore, it is suggested to start off with a dose of 40 mg, gradually working up to anywhere between...

As the popularity of medical cannabis and hemp-infused products increases, so too are the different ways in which you can take it - from oils and tinctures, to gummies, creams, vapes, teas, and even toothpicks. 

 

No wonder then that an increasing number of people are starting to question the efficacy if what many consider more gimmicky products. But also, what IS the best and most effective way to take medical cannabis and hemp products?

Anxiety-related disorders are becoming increasingly common, with 1 in 6 people in the United Kingdom alone, reporting symptoms of anxiety and/or depression each week.  The usual course of treatment often includes heavy duty antidepressants (e.g. duloxetine, venlafaxine and desvenlafaxine), selective serotonin reuptake inhibitors (SSRIs) (e.g. citalopram, fluoxetine, and paroxetine) as well as tranquilizers (the most popular of these being benzodiazepines).

If you're interested in CBD for help with Anxiety, you can shop our collection of suitable Kanaco products here

The ACI report went on to say: “In this independent study, we blind tested over the counter CBD products available in the UK,” explains Professor Saoirse O’Sullivan, The ACI Science Lead. “As has been observed in other countries, we found that only 38% of CBD products were within 10% of the advertised CBD content (one product actually had no CBD in it), and more than half of the products had measurable levels of the controlled substances Δ9-tetrahydrocannabinol (THC) or cannabinol (CBN).”

When will cannabis be legalised in the UK?

Cannabis does have some negatives when used regularly but the same can be said for many substances like alcohol, nicotine, and caffeine. 

It's no secret that the strength of cannabis has increased over recent years

"Things have changed a lot in the last 5 years. Injuries and constant travel take their toll on your body. I’m much more conscious now that this body has to last me a lot longer than being a sponsored skateboarder. So i’ve become far more interested in all aspects of my health, Mentally and physically. I try to eat well, sleep well and just generally give my brain and body the love and time that it needs."
 A child with ADHD has differences in the way in which their brain develops, where the resulting pattern of brain activity affects the persons ability to sustain attention and/or exert self control.  This often leads to an inability to sit still...
The ECS plays a pivotal role in the body, with CB1 and CB2 receptors being distributed throughout the body.  Being involved in regulating a variety of physiological and cognitive process including, appetite, pain-sensation, mood, memory, immune function, memory and even...

Top 5 Innovations in the CBD Industry As with any new industry, the need to grow and become more innovative is starting to hit the CBD industry from all sides. New technologies and products are...

How CBD Interacts with the Human Body In today’s fast-changing industry of cannabis and marijuana, CBD— or cannabidiol—is a hot topic. While it’s a very common term in the industry, many people don’t know what...

By now, you've likely heard of CBD - but what is all the hype about? This article takes a look at some of the science of how CBD interacts with the human body.

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