Cannabinoids can modulate these immune reactions, with some studies suggesting that they can act as either an immunosuppressant, but also immune-boosting effects. In other words, on the one hand, cannabinoids have the potential to relieve symptoms of patients with over-active immune systems, suffering from autoimmune diseases and chronic inflammation.  On the other hand, they also can help people suffering from immunodeficiency disorders such as HIV, through its ability to boost white blood counts.

This makes for a complicated and dichotomous relationship between cannabinoids and the immune system that is still poorly understood.  In addition, the actions of cannabinoids like cannabidiol (CBD) and tetrahydrocannabinol (THC) are mediated primarily by the...

The Role of the Endocannabinoid System in Pain & Inflammation

The role of the endocannabinoid system (ECS) in pain control and symptom relief has been repeatedly demonstrated due to a certain level of independent control and mediation it exerts in the central nervous system and pain signalling system.  Data from various animal studies and clinical trials have shown that the ECS and its primary ligands (a.k.a. endocannabinoids) play a role in pain and pain relief by mediating not only the CB1 and CB2 cannabinoid receptors but also other receptors involved with pain signalling. 

Endocannabinoids, Phytocannabinoids & MS

All of us have something known as an endocannabinoid system (ECS) consisting of receptors, neurotransmitters known as endocannabinoids, and enzymes that break these down once they served their purpose (read more about it here ). 

However, endocannabinoids are a special type of neurotransmitter that are able to not only affect “receiver” neurons, but also “sender” neurons.  When a postsynaptic neuron gets triggered, endocannabinoid production is activated, from where they travel “backwards” up the axon towards the presynaptic neuron, functioning like a dimmer-switch that suppresses neurotransmitter release and neural activity.  Essentially, this means that the way in which neural impulses are sent, neurotransmitters are released, and how these are processed by the CNS is primarily mediated by the ECS.

How CBD interacts with other medications, contraindications & side effects

The safety profile of cannabidiol (CBD) has been extensively researched.  Data from studies, laboratory experiments and clinical trials all show that CBD is well tolerated in both animals and humans, even at extremely high dosages.  In fact, to date, not a single report of a CBD overdose or death has been reported.

Let's take a look at how cannabis and black lives intertwine and what needs to change. 

A more up to date 2020 analysis by the ACLU concluded: “Black people are 3.64 times more likely than white people to be arrested for marijuana possession, notwithstanding comparable usage rates.”

The authors reported: “In every single state, black people were more likely to be arrested for marijuana possession, and in some states, Black people were up to...

CBD Oil Dosage for Sleep

In an early study on the effects of CBD on sleep, researchers found dosage that people who do not suffer from sleeping disorders, needed very high doses of around the 600 mg mark while insomniacs only needed doses of a 150 mg to 160 mg of CBD to induce sleep. Therefore, it is suggested to start off with a dose of 40 mg, gradually working up to anywhere between...