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For many herbal vape users, whether new or veteran, deciding on the right vaping temperature setting can be a bit hit and miss.  Too hot, and the beneficial compounds burn and the vapour tastes foul.  Too cold, and nothing happens…

 

But there is another reason why using the right temperature when vaporising hemp flower - you activate the many beneficial compounds hidden inside it.  This is done via a process called decarboxylation.

With the meteoric rise in popularity of cannabidiol (CBD), a certain amount of confusion exists around the differences between hemp and cannabis.  And despite well-meaning CBD brands trying to clear this up, they sometimes end up spreading misinformation and adding to the confusion even more.

In this article we are going to explore the actual differences between cannabis and hemp, how marijuana fits into the mix and look at some of the most common misconceptions surrounding cannabis, hemp and marijuana.

Cannabinoids can modulate these immune reactions, with some studies suggesting that they can act as either an immunosuppressant, but also immune-boosting effects. In other words, on the one hand, cannabinoids have the potential to relieve symptoms of patients with over-active immune systems, suffering from autoimmune diseases and chronic inflammation.  On the other hand, they also can help people suffering from immunodeficiency disorders such as HIV, through its ability to boost white blood counts.

 

This makes for a complicated and dichotomous relationship between cannabinoids and the immune system that is still poorly understood.  In addition, the actions of cannabinoids like cannabidiol (CBD) and tetrahydrocannabinol (THC) are mediated primarily by the...

The authors of the study said these findings are important in light of major policy changes surrounding the production and sale of cannabis products, as well as increases in the number of people entering treatment for cannabis use disorders and the absence of recommended treatments for this.

Dr Tom Freeman, the study's lead author and Director of the Addiction and Mental Health Group at the University of Bath, UK, said: "Our study provides the first causal evidence to support cannabidiol, or CBD, as a treatment for cannabis use disorders.

“This is encouraging, as there are currently no drug treatments for cannabis addiction.

“CBD products are widely available in many countries but we would not advise people to self-medicate with these products. People with concerns about their cannabis use should always speak to a healthcare professional in the first instance."

The Role of the Endocannabinoid System in Pain & Inflammation

The role of the endocannabinoid system (ECS) in pain control and symptom relief has been repeatedly demonstrated due to a certain level of independent control and mediation it exerts in the central nervous system and pain signalling system.  Data from various animal studies and clinical trials have shown that the ECS and its primary ligands (a.k.a. endocannabinoids) play a role in pain and pain relief by mediating not only the CB1 and CB2 cannabinoid receptors but also other receptors involved with pain signalling. 

Endocannabinoids, Phytocannabinoids & MS

All of us have something known as an endocannabinoid system (ECS) consisting of receptors, neurotransmitters known as endocannabinoids, and enzymes that break these down once they served their purpose (read more about it here ). 

However, endocannabinoids are a special type of neurotransmitter that are able to not only affect “receiver” neurons, but also “sender” neurons.  When a postsynaptic neuron gets triggered, endocannabinoid production is activated, from where they travel “backwards” up the axon towards the presynaptic neuron, functioning like a dimmer-switch that suppresses neurotransmitter release and neural activity.  Essentially, this means that the way in which neural impulses are sent, neurotransmitters are released, and how these are processed by the CNS is primarily mediated by the ECS.

The extracts were low in THC, a cannabinoid (like CBD) found in the marijuana plant that induces a ‘high’.

The researchers then tested the effect the extracts had an angiotensin-converting enzyme 2(ACE2) - the receptors needed for the virus to enter cells in the body.

The results showed hemp extracts high in CBD may help block protein that give a “gateway” for COVID-19 to enter a person’s cells.

How CBD interacts with other medications, contraindications & side effects

The safety profile of cannabidiol (CBD) has been extensively researched.  Data from studies, laboratory experiments and clinical trials all show that CBD is well tolerated in both animals and humans, even at extremely high dosages.  In fact, to date, not a single report of a CBD overdose or death has been reported.

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